Immunoglobulins (IgG’s) can be used as heterophilic blocking agents for many in vitro diagnostic applications to prevent false positive results.
The addition of immunoglobulins are intended to block undesirable reactivity within the assay. A well-known example of heterophilic reactivity is HAMA. Mouse IgG has the capacity to reduce HAMA reactivity when testing human patient samples with mouse monoclonal antibodies.
Specifications of Bulk IgGs
Purification: Protein A or Protein G
Purity: 95% based on SDS PAGE
Concentration: 8-12 mg/ml
Form: Liquid or Lyophilized
Unit Sizes: 100 mg / 500 mg / 1 gram / 1 kg